Vulvar intraepithelial neoplasia (VIN) treatment in 736 Oncology clinics worldwide

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736 clinics specializing in Oncology providing treatment of Vulvar intraepithelial neoplasia (VIN) Vulvar intraepithelial neoplasia (VIN) is a precancerous condition where abnormal cells are found in the skin of the vulva. It may cause itching, pain, or changes in the vulvar appearance. Treatment includes local excision or laser ablation to prevent progression to vulvar cancer.
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disease worldwide.

Africa · 12
Americas · 142
Asia · 222
Europe · 329
Oceania · 31
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Africa · 12 Americas · 142 Asia · 222 Europe · 329 Oceania · 31
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Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $1,823
  2. Radical vulvectomy
    ≈ $915
  3. Conization
    $580 - $897
  4. Open hysterectomy
    $1,914 - $3,194
  5. Loop electrosurgical excision procedure (LEEP)
    ≈ $211
  6. Total laparoscopic hysterectomy (TLH)
    $2,434 - $4,468
  7. Myomectomy
    $831 - $1,219
  8. Radical trachelectomy
    $1,914 - $2,302
  9. Laparoscopic adnexectomy
    $1,537 - $2,554
photo
Riga, Latvia
Specializations: Oncology
We are a private gynecological clinic in Riga that provides high-quality care for women and their health. Our professional specialists will provide you with quality read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $1,823
  2. Radical vulvectomy
    ≈ $915
  3. Hemicolectomy
    ≈ $2,215
  4. Rectum anterior resection
    ≈ $1,159
  5. Conization
    ≈ $1,087
  6. Open hysterectomy
    ≈ $1,669
  7. Loop electrosurgical excision procedure (LEEP)
    $197
  8. Total laparoscopic hysterectomy (TLH)
    from $2,554
  9. Laparoscopic cholecystectomy
    ≈ $1,268
photo
Riga, Latvia
Specializations: Thoracic surgery, Oncology
Our highly qualified specialists have experience in clinical and scientific work. We use laparoscopic operations in the surgical treatment of ovarian cysts, fibroids, uterus read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $4,737
  2. Radical vulvectomy
    ≈ $10,365
  3. Hemicolectomy
    ≈ $19,697
  4. Rectum anterior resection
    ≈ $16,618
  5. Radical prostatectomy
    ≈ $17,065
  6. Transurethral resection of the prostate (TURP)
    ≈ $8,578
  7. Conization
    ≈ $3,507
  8. Open hysterectomy
    ≈ $8,890
  9. Radical nephrectomy
    ≈ $20,754
photo
Dubai, United Arab Emirates
Specializations: Thoracic surgery, Oncology
Languages: English, Arabic
Mediclinic City Hospital’s Comprehensive Cancer Centre (CCC), is Dubai’s most advanced facility for the diagnosis and treatment of cancer. Built in collaboration with Mediclinic Middle read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $1,886
  2. Radical vulvectomy
    ≈ $4,922
  3. Hemicolectomy
    ≈ $9,535
  4. Rectum anterior resection
    ≈ $6,707
  5. Radical prostatectomy
    ≈ $7,371
  6. Transurethral resection of the prostate (TURP)
    ≈ $3,526
  7. Conization
    ≈ $1,520
  8. Open hysterectomy
    ≈ $3,126
  9. Radical nephrectomy
    ≈ $8,894
photo
Medina, Saudi Arabia
Specializations: Vascular surgery, Thoracic surgery, Oncology
King Faisal Specialist Hospital & Research Centre (Gen. Org) Madinah (KFSH&RC-M) is the latest addition to our internationally recognized organization. Our mission at KFSH&RC-M is read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $4,893
  2. Radical vulvectomy
    ≈ $7,656
  3. Radical prostatectomy
    ≈ $16,436
  4. Transurethral resection of the prostate (TURP)
    ≈ $7,802
  5. Conization
    ≈ $3,393
  6. Open hysterectomy
    ≈ $5,269
  7. Radical nephrectomy
    ≈ $17,827
  8. Loop electrosurgical excision procedure (LEEP)
    ≈ $2,279
  9. Total laparoscopic hysterectomy (TLH)
    ≈ $6,127
photo
Toulouse, France
Specializations: Thoracic surgery, Oncology
Languages: English, German, Spanish; Castilian
The IUCT Oncopole comprises the Institut Claudius Regaud, a cancer center, and several teams from Toulouse University Hospital Center. The two institutions offer the expertise read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $5,915
  2. Radical vulvectomy
    ≈ $10,151
  3. Hemicolectomy
    ≈ $23,214
  4. Rectum anterior resection
    ≈ $22,108
  5. Radical prostatectomy
    ≈ $21,050
  6. Transurethral resection of the prostate (TURP)
    ≈ $9,719
  7. Conization
    ≈ $4,491
  8. Open hysterectomy
    ≈ $8,584
  9. Radical nephrectomy
    ≈ $23,716
photo
Milan, Italy
Specializations: Cardiac surgery, Vascular surgery, Thoracic surgery, Oncology
Languages: Arabic, English, Russian
The IEO (European Institute of Oncology) is one of the world's most prestigious hospitals and the fastest growing comprehensive cancer centre in Europe. IEO integrates read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $2,553
  2. Radical vulvectomy
    ≈ $4,897
  3. Radical prostatectomy
    ≈ $9,135
  4. Transurethral resection of the prostate (TURP)
    ≈ $4,499
  5. Conization
    ≈ $2,096
  6. Open hysterectomy
    ≈ $3,478
  7. Radical nephrectomy
    ≈ $11,549
  8. Loop electrosurgical excision procedure (LEEP)
    ≈ $1,351
  9. Total laparoscopic hysterectomy (TLH)
    ≈ $3,797
photo
Medellín, Colombia
Specializations: Cardiac surgery, Oncology
At Clínica del Prado we are committed to protecting the life, integrity and health of our employees, contractors, third parties, visitors and interested parties, as read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $898
  2. Radical vulvectomy
    ≈ $1,950
  3. Brachytherapy for prostate cancer
    $5,059
  4. Stereotactic radiation therapy (SRT)
    $2,761
  5. Radioactive Iodine therapy for thyroid cancer
    $1,573
  6. Hemicolectomy
    $1,341 - $2,335
  7. Rectum anterior resection
    $1,341 - $2,335
  8. Radical prostatectomy
    ≈ $2,751
  9. Transurethral resection of the prostate (TURP)
    ≈ $1,864
photo
Kazan, Russia
Specializations: Cardiac surgery, Vascular surgery, Thoracic surgery, Oncology
GAUZ "Republican Clinical Oncological Dispensary of the Ministry of Health of the Republic of Tatarstan" named after Professor M.Z. Sigal "is one of the largest read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $4,893
  2. Radical vulvectomy
    ≈ $7,656
  3. Hemicolectomy
    ≈ $16,934
  4. Rectum anterior resection
    ≈ $18,273
  5. Radical prostatectomy
    ≈ $16,436
  6. Transurethral resection of the prostate (TURP)
    ≈ $7,802
  7. Conization
    ≈ $3,393
  8. Open hysterectomy
    ≈ $5,269
  9. Radical nephrectomy
    ≈ $17,827
photo
Marseille, France
Specializations: Vascular surgery, Thoracic surgery, Oncology
The Paoli-Calmettes Institute (IPC) is a center for the fight against cancer, a member of the Unicancer group , governed by the public health code. read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $2,726
  2. Radical vulvectomy
    ≈ $4,750
  3. Conization
    ≈ $2,102
  4. Open hysterectomy
    ≈ $2,603
  5. Loop electrosurgical excision procedure (LEEP)
    ≈ $1,171
  6. Total laparoscopic hysterectomy (TLH)
    $1,577
  7. Laparoscopic cholecystectomy
    ≈ $1,539
  8. Total gastrectomy
    ≈ $18,779
  9. Total thyroidectomy
    ≈ $4,847
photo
Reynosa, Mexico
Specializations: Cardiac surgery, Vascular surgery, Oncology
Languages: English
The quality of CHRISTUS MUGUERZA on the Mexican border At CHRISTUS MUGUERZA Hospital Reynosa we provide high quality medical services to the Tamaulipas border community read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $1,036
  2. Radical vulvectomy
    ≈ $2,290
  3. Hemicolectomy
    ≈ $4,514
  4. Rectum anterior resection
    ≈ $3,484
  5. Conization
    ≈ $734
  6. Open hysterectomy
    ≈ $1,642
  7. Loop electrosurgical excision procedure (LEEP)
    ≈ $411
  8. Total laparoscopic hysterectomy (TLH)
    ≈ $1,793
  9. Laparoscopic cholecystectomy
    ≈ $1,447
photo
Chittagong, Bangladesh
Specializations: Thoracic surgery, Oncology
Chattogram Maa-O-Shishu Hospital is a 650-bedded hospital, which includes Paediatrics Medicine, Neonatology, Pediatric Surgery, Paediatric Neorology, General Surgery, Obstetrics & Gynaecology, Medicine & it's sub-specialists. read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $2,060
  2. Radical vulvectomy
    ≈ $4,338
  3. Conization
    ≈ $1,326
  4. Open hysterectomy
    ≈ $3,241
  5. Loop electrosurgical excision procedure (LEEP)
    from $764
  6. Total laparoscopic hysterectomy (TLH)
    ≈ $4,182
  7. Lumpectomy
    ≈ $1,429
  8. Myomectomy
    ≈ $1,326
  9. Simple mastectomy
    ≈ $3,604
photo
Belgrade, Serbia
Specializations: Thoracic surgery, Orthopedic surgery, Oncology
In one place, you are provided with the highest quality medical assistance by leading specialists and subspecialists from almost all areas of modern medicine. Euromedik read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $1,398
  2. Radical vulvectomy
    ≈ $1,017
  3. Hemicolectomy
    ≈ $6,960
  4. Rectum anterior resection
    ≈ $7,278
  5. Radical prostatectomy
    ≈ $6,617
  6. Transurethral resection of the prostate (TURP)
    ≈ $2,479
  7. Conization
    ≈ $778
  8. Open hysterectomy
    ≈ $2,568
  9. Radical nephrectomy
    ≈ $9,083
photo
Esztergom, Hungary
Specializations: Orthopedic surgery, Oncology
Languages: English, German
The Vaszary Kolos Hospital is more than 100 years old, pavilion system, in the eastern corner of Komárom-Esztergom county, 46 km from Budapest. It is read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $5,147
  2. Radical vulvectomy
    ≈ $10,061
  3. Conization
    ≈ $3,157
  4. Open hysterectomy
    from $8,800
  5. Radical nephrectomy
    ≈ $13,697
  6. Loop electrosurgical excision procedure (LEEP)
    ≈ $1,715
  7. Total laparoscopic hysterectomy (TLH)
    from $8,800
  8. Parotidectomy
    ≈ $6,383
  9. Lumpectomy
    ≈ $4,855
photo
Griffith, Australia
Specializations: Orthopedic surgery, Oncology
St Vincent’s Hospitals Australia has a rich tradition of providing progressive and excellent health care. We combine the latest technology with exceptional and compassionate medical, read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $5,147
  2. Radical vulvectomy
    ≈ $10,061
  3. Hemicolectomy
    $14,008
  4. Rectum anterior resection
    ≈ $16,897
  5. Radical prostatectomy
    ≈ $15,557
  6. Transurethral resection of the prostate (TURP)
    ≈ $6,032
  7. Conization
    ≈ $3,157
  8. Open hysterectomy
    from $8,800
  9. Radical nephrectomy
    ≈ $13,697
photo
Melbourne, Australia
Specializations: Thoracic surgery, Orthopedic surgery, Oncology
Languages: Arabic, Croatian, Italian, Serbian, Somali, Turkish, Vietnamese, Spanish; Castilian, Chinese, Greek, Modern
St Vincent’s Hospitals Australia has a rich tradition of providing progressive and excellent health care. We combine the latest technology with exceptional and compassionate medical, read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $4,893
  2. Radical vulvectomy
    ≈ $7,656
  3. Conization
    ≈ $3,393
  4. Open hysterectomy
    ≈ $5,269
  5. Loop electrosurgical excision procedure (LEEP)
    ≈ $2,279
  6. Total laparoscopic hysterectomy (TLH)
    ≈ $6,127
  7. Myomectomy
    ≈ $5,217
  8. Ovarian transposition
    ≈ $1,043
  9. Radical trachelectomy
    ≈ $5,262
photo
Paris, France
Specializations: Orthopedic surgery, Oncology
Close to other establishments, the privileged quiet location of the Pierre Cherest clinic contributes to the serenity and comfort of our patients. The Ambroise Paré, read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $4,893
  2. Radical vulvectomy
    ≈ $7,656
  3. Hemicolectomy
    ≈ $16,934
  4. Rectum anterior resection
    ≈ $18,273
  5. Radical prostatectomy
    ≈ $16,436
  6. Transurethral resection of the prostate (TURP)
    ≈ $7,802
  7. Conization
    ≈ $3,393
  8. Open hysterectomy
    ≈ $5,269
  9. Radical nephrectomy
    ≈ $17,827
photo
Paris, France
Specializations: Thoracic surgery, Orthopedic surgery, Oncology
The Ambroise Paré, Pierre Cherest and Hartmann Clinics bring together specialized multidisciplinary teams. Regarding the financial aspect of care, every effort is made to ensure read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $2,576
  2. Radical vulvectomy
    ≈ $4,574
  3. Hemicolectomy
    ≈ $9,759
  4. Rectum anterior resection
    ≈ $10,037
  5. Radical prostatectomy
    ≈ $8,587
  6. Transurethral resection of the prostate (TURP)
    ≈ $4,222
  7. Conization
    ≈ $1,971
  8. Open hysterectomy
    ≈ $3,620
  9. Radical nephrectomy
    ≈ $9,419
photo
Buenos Aires, Argentina
Specializations: Cardiac surgery, Thoracic surgery, Orthopedic surgery, Oncology
As of March 14, 1994, the Alexander Fleming Institute opened its doors to medical and scientific excellence. Maximum technical-scientific level and comfort in one of read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $5,147
  2. Radical vulvectomy
    ≈ $10,061
  3. Hemicolectomy
    ≈ $13,628
  4. Rectum anterior resection
    ≈ $16,897
  5. Radical prostatectomy
    ≈ $15,557
  6. Transurethral resection of the prostate (TURP)
    ≈ $6,032
  7. Conization
    ≈ $3,157
  8. Open hysterectomy
    ≈ $8,248
  9. Loop electrosurgical excision procedure (LEEP)
    ≈ $1,715
photo
Werribee, Australia
Specializations: Vascular surgery, Thoracic surgery, Orthopedic surgery, Oncology
Mercy Health – Health Services provides care for people in hospitals, clinics and community-based healthcare facilities in Victoria and southern New South Wales.Werribee Mercy Hospital read more
Prices for popular procedures:
  1. Partial vulvectomy
    ≈ $5,147
  2. Radical vulvectomy
    ≈ $10,061
  3. Hemicolectomy
    ≈ $13,628
  4. Rectum anterior resection
    ≈ $16,897
  5. Conization
    ≈ $3,157
  6. Open hysterectomy
    ≈ $8,248
  7. Loop electrosurgical excision procedure (LEEP)
    ≈ $1,715
  8. Total laparoscopic hysterectomy (TLH)
    ≈ $8,398
  9. Total gastrectomy
    ≈ $21,692
photo
Brighton, Australia
Specializations: Cardiac surgery, Vascular surgery, Thoracic surgery, Orthopedic surgery, Oncology
Cabrini Brighton is a boutique hospital located in the heart of Bayside, open 24 hours, seven days a week.This 138-bed facility specialises in oncology services, read more

Clinics grouping by rating

Clinic with the highest rating of 5 — Berkana clinic in Moscow, Russia and 5 more, clinic with the most reviews number of 35757 — Aster CMI hospital in Bengaluru, India.

With rating 4.0 and over — 265 clinics .

Countries with the highest number of clinics treating the diseases:

Vulvar intraepithelial neoplasia (VIN):

Related procedures:

Procedures are likely to be used for Vulvar intraepithelial neoplasia (VIN) treatment: Laser gynecological vaporization, Laser therapy for cancer, Partial vulvectomy, and Radical vulvectomy .

Vulvar Intraepithelial Neoplasia (VIN): Overview

Disease Types

What is the vulvar intraepithelial neoplasia?

Vulvar intraepithelial neoplasia (VIN) is a pre-cancerous condition affecting the vulva, the external female genitalia. This condition involves abnormal cellular growth and development within the vulvar skin, which can potentially progress to vulvar cancer if left untreated. VIN is classified into three distinct grades (VIN 1, VIN 2, and VIN 3) based on the severity of the abnormal cell changes. Interestingly, VIN 1 is often excluded from this categorization as it resolves without intervention. While VIN is considered a relatively rare condition, its timely diagnosis and appropriate management are crucial to prevent the progression to invasive vulvar cancer.

VIN predominantly affects women during their reproductive years, but it can occur at any age. Notably, the incidence of VIN has been on the rise in recent years, which can be attributed to increased awareness and more prevalent screening practices. In the United States alone, approximately 5,000 women are diagnosed with VIN annually, highlighting the importance of understanding this condition and its management [Ayala & Fatehi, 2022].

Causes & Risk Factors

What is the primary issue of vulvar intraepithelial neoplasia?

The exact cause of VIN is not fully understood, but researchers have identified several key risk factors. Human Papillomavirus (HPV), particularly types 16 and 18, is detected in over 80% of VIN cases, and persistent HPV infection significantly increases the likelihood of developing this condition. Age also plays a role, as VIN is most common in women aged 30 to 50, although it can occur at any age. Smoking habits are another significant factor, as smokers have a two to three times higher risk of developing VIN compared to non-smokers.

Immunosuppression, such as from HIV or certain medications that weaken the immune system, can also increase the risk of VIN. Additionally, individuals with chronic vulvar conditions, including lichen sclerosus and chronic vulvitis, are more susceptible to developing this pre-cancerous condition. Finally, a history of cervical or vulvar cancer further elevates the risk for VIN in women.

Clinical Manifestation & Symptoms

What signs should one anticipate while suspecting vulvar intraepithelial neoplasia?

The symptoms of vulvar intraepithelial neoplasia can vary significantly, but patients often experience a range of standard signs. Persistent itching in the vulvar region is a frequent complaint. Many individuals also report discomfort or pain, especially during sexual intercourse. Changes in the skin's color or texture, such as areas that appear white, red, dark brown, or feel rough or thickened, are also common. Patients may also notice the presence of raised or flat lesions that may bleed or become ulcerated.

Diagnostic Route

When, where, and how should vulvar intraepithelial neoplasia be detected?

Diagnosing vulvar intraepithelial neoplasia (VIN) involves a comprehensive approach. First, a healthcare provider will thoroughly examine the vulva to identify any abnormal areas.

Next, the doctor may perform a colposcopic procedure. This involves using a specialized instrument called a colposcope to magnify and closely examine the vulva and cervix, searching for signs of abnormal cell growth.

If the physician notices any areas of concern during the physical exam or colposcopy, they will likely recommend a biopsy. This involves taking a small sample of the suspicious tissue and sending it to a laboratory for microscopic analysis. The biopsy results can confirm the diagnosis of VIN and provide information about the severity of the condition.

It's important to note that routine screening for VIN is not typically recommended. However, women with symptoms or known risk factors, such as a history of cervical or vulvar cancer, should be sure to undergo regular gynecological exams [ASCCP, 2020].

Treatment Approaches

What are the options for managing vulvar intraepithelial neoplasia?

The primary goal of VIN treatment is to eliminate the abnormal cells and prevent the progression to cancer. The choice of treatment approach depends on various factors, including the severity and extent of the condition, the patient's preferences, and the presence of symptoms.

Surgical interventions can be highly effective in managing VIN. Wide local excision, which involves the surgical removal of the abnormal tissue along with a margin of healthy tissue, has a high success rate and is particularly effective in preventing recurrence. Laser ablation, a less invasive technique that uses a laser to destroy the abnormal cells, is another option, although it carries a higher recurrence risk than excision.

For patients with extensive or recurrent VIN, a more extensive surgical procedure, known as vulvectomy, may be necessary, involving the partial or complete removal of the vulva.

In addition to surgical treatments, therapeutical approaches can also effectively manage VIN. Topical therapies, such as imiquimod cream, have been shown to stimulate the immune system to target and eliminate abnormal cells, with response rates ranging from 50% to 70%. Cidofovir, an antiviral drug applied topically, has also demonstrated promising results, with approximately 60% to 80% response rates.

Another treatment option is photodynamic therapy (PDT), which involves the application of a photosensitizing agent to the affected area, followed by exposure to a specific wavelength of light. This less invasive approach has shown 60% to 75% efficacy in treating VIN.

VIN prevention

The HPV vaccine has shown tremendous promise in reducing the risk of developing vulvar intraepithelial neoplasia (VIN). Research indicates that by preventing HPV infection, the vaccine can potentially decrease the incidence of VIN by up to 90% in vaccinated populations.

Prognosis & Follow-up

How does cutting-edge science improve the lifespan and quality of life for those with vulvar intraepithelial neoplasia?

With early detection and appropriate treatment, the prognosis for women with VIN is generally reasonable. The risk of progression to invasive vulvar cancer is low when VIN is treated promptly. Advances in minimally invasive therapies, such as laser ablation and photodynamic therapy, have improved outcomes and shortened recovery times, enhancing the quality of life for patients.

Regular follow-up is essential for women treated for VIN. Despite the available treatment options for VIN, the condition does have a high recurrence rate, ranging from 20% to 50%.

The follow-up protocol typically includes physical examinations every 3-6 months for the first two years, then annually. Colposcopy and biopsy are performed as needed based on symptoms or findings during physical exams. Patients are encouraged to conduct regular self-examinations and promptly report any new symptoms to their healthcare team.

  • Isabella Gonzalez, M.D.
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