Duodenal cancer treatment in 844 Oncology clinics worldwide

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844 clinics specializing in Oncology providing treatment of Duodenal cancer Duodenal cancer is a rare malignancy that originates in the first part of the small intestine, called the duodenum. It may cause abdominal pain, weight loss, and may require surgery, chemotherapy, or radiation therapy for treatment depending on the stage and extent of the cancer.
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disease worldwide.

Africa · 13
Americas · 175
Asia · 263
Europe · 357
Oceania · 36
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Africa · 13 Americas · 175 Asia · 263 Europe · 357 Oceania · 36
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Prices for popular procedures:
  1. Chemotherapy for colorectal cancer
    by request
  2. Chemotherapy for melanoma
    by request
  3. Chemotherapy for endometrial cancer
    by request
  4. Chemotherapy for gallbladder cancer
    by request
  5. Chemotherapy for bone cancer
    by request
  6. Chemotherapy for eye cancer
    by request
  7. Chemotherapy for myeloma
    by request
  8. Chemotherapy for non-melanoma skin cancer
    by request
  9. Chemotherapy for testicular cancer
    by request
photo
Belo Horizonte, Brazil
Specializations: Oncology
Founded in 1999, Oncocentro was born with the purpose of offering an integral, welcoming and interdisciplinary service. Over the years, it has become a reference read more
Prices for popular procedures:
  1. Radiation therapy
    $2,552
  2. Chemotherapy for colorectal cancer
    by request
  3. Radiation therapy for breast cancer
    $2,169 - $3,828
  4. Radiotherapy for prostate cancer
    $2,552
  5. LINAC based stereotactic radiosurgery
    $2,552
  6. Intensity-modulated radiation therapy (IMRT)
    $2,552
  7. Stereotactic radiation therapy (SRT)
    $2,552
  8. Radiosurgery
    $2,552
  9. Intracavitary brachytherapy
    $2,297
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Balashikha, Russia
Specializations: Oncology
The PET-Technology oncology center in Balashikha was designed, built and equipped as part of a public-private partnership with the Government of the Moscow Region, the read more
Prices for popular procedures:
  1. Radiation therapy
    $2,552
  2. Chemotherapy for colorectal cancer
    by request
  3. Radiation therapy for breast cancer
    $2,169 - $3,828
  4. Radiotherapy for prostate cancer
    $2,552
  5. LINAC based stereotactic radiosurgery
    $2,552
  6. Intensity-modulated radiation therapy (IMRT)
    $2,552
  7. Stereotactic radiation therapy (SRT)
    $2,552
  8. Radiosurgery
    $2,552
  9. Intracavitary brachytherapy
    $2,297
photo
Podolsk, Russia
Specializations: Oncology
The PET-Technology Cancer Radiology Center in Podolsk is a modern, comfortable medical facility for patients with any stage of the disease. The center has a read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $718
  2. Duodenectomy
    ≈ $1,878
  3. Jejunostomy
    ≈ $746
  4. Pancreaticoduodenectomy
    ≈ $12,813
  5. Hemicolectomy
    ≈ $2,254
  6. Rectum anterior resection
    ≈ $1,180
  7. Conization
    ≈ $1,106
  8. Open hysterectomy
    ≈ $1,698
  9. Loop electrosurgical excision procedure (LEEP)
    $200
photo
Riga, Latvia
Specializations: Thoracic surgery, Oncology
Our highly qualified specialists have experience in clinical and scientific work. We use laparoscopic operations in the surgical treatment of ovarian cysts, fibroids, uterus read more
Prices for popular procedures:
  1. Chemotherapy for colorectal cancer
    by request
  2. Chemotherapy for liver cancer
    by request
  3. Chemotherapy for brain cancer
    by request
  4. Chemotherapy for lymphoma
    by request
  5. Chemotherapy for gallbladder cancer
    by request
  6. Chemotherapy for eye cancer
    by request
  7. Chemotherapy for myeloma
    by request
  8. Chemotherapy for melanoma
    by request
  9. Chemotherapy for non-melanoma skin cancer
    by request
photo
Budapest, Hungary
Specializations: Oncology
In the Oncology Profile of the Internal Medicine and Oncology Clinic patients with so-called solid tumors are treated with medication. The center offers traditional chemotherapy read more
Prices for popular procedures:
  1. Radiation therapy
    by request
  2. Chemotherapy for colorectal cancer
    by request
  3. Radiation therapy for breast cancer
    from $21,750
  4. Radiotherapy for prostate cancer
    from $34,476
  5. Brachytherapy for prostate cancer
    from $53,066
  6. Lumpectomy
    ≈ $7,067
  7. Simple mastectomy
    from $16,915
  8. Partial mastectomy
    from $19,191
  9. Radical mastectomy
    from $16,915
photo
Helsinki, Finland
Specializations: Oncology
Docrates Cancer Center, based in Helsinki, Finland, is a leading international treatment facility specialising in the diagnostics, treatment and follow-up of cancers. The hospital opened read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $12,492
  2. Duodenectomy
    ≈ $4,730
  3. Jejunostomy
    ≈ $8,707
  4. Pancreaticoduodenectomy
    ≈ $33,183
  5. Radiation therapy
    by request
  6. Chemotherapy for colorectal cancer
    by request
  7. Hemicolectomy
    ≈ $19,703
  8. Rectum anterior resection
    ≈ $16,634
  9. Radical prostatectomy
    ≈ $17,069
photo
Dubai, United Arab Emirates
Specializations: Thoracic surgery, Oncology
Languages: English, Arabic
Mediclinic City Hospital’s Comprehensive Cancer Centre (CCC), is Dubai’s most advanced facility for the diagnosis and treatment of cancer. Built in collaboration with Mediclinic Middle read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $6,470
  2. Duodenectomy
    ≈ $897
  3. Jejunostomy
    ≈ $3,729
  4. Pancreaticoduodenectomy
    ≈ $16,731
  5. Radiation therapy
    by request
  6. Chemotherapy for colorectal cancer
    by request
  7. Hemicolectomy
    ≈ $9,550
  8. Rectum anterior resection
    ≈ $6,731
  9. Radical prostatectomy
    ≈ $7,389
photo
Medina, Saudi Arabia
Specializations: Vascular surgery, Thoracic surgery, Oncology
King Faisal Specialist Hospital & Research Centre (Gen. Org) Madinah (KFSH&RC-M) is the latest addition to our internationally recognized organization. Our mission at KFSH&RC-M is read more
Prices for popular procedures:
  1. Radiation therapy
    by request
  2. Radical prostatectomy
    ≈ $16,764
  3. Transurethral resection of the prostate (TURP)
    ≈ $7,952
  4. Conization
    ≈ $3,458
  5. Open hysterectomy
    ≈ $5,369
  6. Radical nephrectomy
    ≈ $18,175
  7. Loop electrosurgical excision procedure (LEEP)
    ≈ $2,322
  8. Total laparoscopic hysterectomy (TLH)
    ≈ $6,251
  9. Parotidectomy
    ≈ $5,128
photo
Toulouse, France
Specializations: Thoracic surgery, Oncology
Languages: English, German, Spanish; Castilian
The IUCT Oncopole comprises the Institut Claudius Regaud, a cancer center, and several teams from Toulouse University Hospital Center. The two institutions offer the expertise read more
Prices for popular procedures:
  1. Radiation therapy
    by request
  2. Chimeric antigen receptor (CAR) T-cell therapy
    by request
  3. Immune checkpoint inhibitors
    by request
  4. Monoclonal antibodies therapy (mAbs)
    by request
  5. Natural killer (NK) cell therapy
    by request
photo
São Paulo, Brazil
Specializations: Oncology
Occupying a total area of ​​1,550 m2, we have an infrastructure specially built to ensure the well-being of patients during cancer treatment. Humanism was the read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $17,678
  2. Duodenectomy
    ≈ $6,551
  3. Jejunostomy
    ≈ $11,833
  4. Pancreaticoduodenectomy
    ≈ $47,037
  5. Chemotherapy for colorectal cancer
    by request
  6. Hemicolectomy
    ≈ $25,939
  7. Rectum anterior resection
    ≈ $21,889
  8. Laparoscopic cholecystectomy
    ≈ $9,557
  9. Total gastrectomy
    ≈ $41,512
photo
London, United Kingdom
Specializations: Cardiac surgery, Thoracic surgery, Oncology
Newsweek ranks Mayo Clinic in the United States as the best hospital in the world. U.S. News & World Report has ranked it No. 1 read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $15,498
  2. Duodenectomy
    ≈ $4,587
  3. Jejunostomy
    ≈ $7,902
  4. Pancreaticoduodenectomy
    ≈ $39,946
  5. Radiation therapy
    by request
  6. Chemotherapy for colorectal cancer
    by request
  7. Hemicolectomy
    ≈ $23,647
  8. Rectum anterior resection
    ≈ $22,542
  9. Radical prostatectomy
    ≈ $21,453
photo
Milan, Italy
Specializations: Cardiac surgery, Vascular surgery, Thoracic surgery, Oncology
Languages: Arabic, English, Russian
The IEO (European Institute of Oncology) is one of the world's most prestigious hospitals and the fastest growing comprehensive cancer centre in Europe. IEO integrates read more
Prices for popular procedures:
  1. Pancreaticoduodenectomy
    ≈ $4,312
  2. Radiation therapy
    $198 - $7,068
  3. Chemotherapy for colorectal cancer
    by request
  4. Brachytherapy for prostate cancer
    $5,303
  5. Stereotactic radiation therapy (SRT)
    $2,894
  6. Radioactive Iodine therapy for thyroid cancer
    $1,649
  7. Hemicolectomy
    $1,406 - $2,447
  8. Rectum anterior resection
    $1,406 - $2,447
  9. Radical prostatectomy
    ≈ $2,883
photo
Kazan, Russia
Specializations: Cardiac surgery, Vascular surgery, Thoracic surgery, Oncology
GAUZ "Republican Clinical Oncological Dispensary of the Ministry of Health of the Republic of Tatarstan" named after Professor M.Z. Sigal "is one of the largest read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $16,441
  2. Duodenectomy
    ≈ $2,124
  3. Jejunostomy
    ≈ $4,513
  4. Pancreaticoduodenectomy
    ≈ $31,337
  5. Radiation therapy
    by request
  6. Chemotherapy for colorectal cancer
    by request
  7. Hemicolectomy
    ≈ $17,250
  8. Rectum anterior resection
    ≈ $18,649
  9. Radical prostatectomy
    ≈ $16,764
photo
Marseille, France
Specializations: Vascular surgery, Thoracic surgery, Oncology
The Paoli-Calmettes Institute (IPC) is a center for the fight against cancer, a member of the Unicancer group , governed by the public health code. read more
Prices for popular procedures:
  1. Chemotherapy for colorectal cancer
    by request
  2. Conization
    ≈ $2,068
  3. Open hysterectomy
    ≈ $2,611
  4. Loop electrosurgical excision procedure (LEEP)
    ≈ $1,153
  5. Total laparoscopic hysterectomy (TLH)
    $1,582
  6. Laparoscopic cholecystectomy
    ≈ $1,543
  7. Total gastrectomy
    ≈ $18,454
  8. Total thyroidectomy
    ≈ $4,771
  9. Cholecystectomy
    ≈ $3,060
photo
Reynosa, Mexico
Specializations: Cardiac surgery, Vascular surgery, Oncology
Languages: English
The quality of CHRISTUS MUGUERZA on the Mexican border At CHRISTUS MUGUERZA Hospital Reynosa we provide high quality medical services to the Tamaulipas border community read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $2,630
  2. Duodenectomy
    ≈ $1,358
  3. Jejunostomy
    ≈ $1,718
  4. Pancreaticoduodenectomy
    ≈ $7,281
  5. Chemotherapy for colorectal cancer
    by request
  6. Hemicolectomy
    ≈ $4,516
  7. Rectum anterior resection
    ≈ $3,490
  8. Conization
    ≈ $735
  9. Open hysterectomy
    ≈ $1,644
photo
Chittagong, Bangladesh
Specializations: Thoracic surgery, Oncology
Chattogram Maa-O-Shishu Hospital is a 650-bedded hospital, which includes Paediatrics Medicine, Neonatology, Pediatric Surgery, Paediatric Neorology, General Surgery, Obstetrics & Gynaecology, Medicine & it's sub-specialists. read more
Prices for popular procedures:
  1. Radiation therapy
    by request
  2. Chemotherapy for colorectal cancer
    by request
  3. Radical prostatectomy
    ≈ $10,240
  4. Transurethral resection of the prostate (TURP)
    ≈ $3,151
  5. Radical nephrectomy
    ≈ $6,095
  6. Parotidectomy
    ≈ $1,183
  7. Lumpectomy
    ≈ $1,314
  8. Cervical lymphadenectomy
    ≈ $3,310
  9. Transurethral resection of bladder tumor (TURBT)
    ≈ $2,430
photo
Chennai, India
Specializations: Thoracic surgery, Orthopedic surgery, Oncology
The Cancer Institute (WIA), as you are aware, is a public charitable voluntary institute dedicated to the care of cancer for for the last 60 read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $13,492
  2. Duodenectomy
    ≈ $8,877
  3. Jejunostomy
    ≈ $8,022
  4. Pancreaticoduodenectomy
    ≈ $33,070
  5. Chemotherapy for colorectal cancer
    by request
  6. Hemicolectomy
    $14,011
  7. Rectum anterior resection
    ≈ $16,901
  8. Radical prostatectomy
    ≈ $15,560
  9. Transurethral resection of the prostate (TURP)
    ≈ $6,033
photo
Melbourne, Australia
Specializations: Thoracic surgery, Orthopedic surgery, Oncology
Languages: Arabic, Croatian, Italian, Serbian, Somali, Turkish, Vietnamese, Spanish; Castilian, Chinese, Greek, Modern
St Vincent’s Hospitals Australia has a rich tradition of providing progressive and excellent health care. We combine the latest technology with exceptional and compassionate medical, read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $16,441
  2. Duodenectomy
    ≈ $2,124
  3. Jejunostomy
    ≈ $4,513
  4. Pancreaticoduodenectomy
    ≈ $31,337
  5. Radiation therapy
    by request
  6. Chemotherapy for colorectal cancer
    by request
  7. Hemicolectomy
    ≈ $17,250
  8. Rectum anterior resection
    ≈ $18,649
  9. Radical prostatectomy
    ≈ $16,764
photo
Paris, France
Specializations: Thoracic surgery, Orthopedic surgery, Oncology
The Ambroise Paré, Pierre Cherest and Hartmann Clinics bring together specialized multidisciplinary teams. Regarding the financial aspect of care, every effort is made to ensure read more
Prices for popular procedures:
  1. Small bowel resection
    ≈ $6,947
  2. Duodenectomy
    ≈ $1,972
  3. Jejunostomy
    ≈ $2,946
  4. Pancreaticoduodenectomy
    ≈ $18,157
  5. Radiation therapy
    by request
  6. Hemicolectomy
    ≈ $9,859
  7. Rectum anterior resection
    ≈ $10,155
  8. Radical prostatectomy
    ≈ $8,684
  9. Transurethral resection of the prostate (TURP)
    ≈ $4,268
photo
Buenos Aires, Argentina
Specializations: Cardiac surgery, Thoracic surgery, Orthopedic surgery, Oncology
As of March 14, 1994, the Alexander Fleming Institute opened its doors to medical and scientific excellence. Maximum technical-scientific level and comfort in one of read more

Clinics grouping by rating

Clinic with the highest rating of 5 — Berkana clinic in Moscow, Russia and 4 more, clinic with the most reviews number of 35757 — Aster CMI hospital in Bengaluru, India.

With rating 4.0 and over — 287 clinics .

Countries with the highest number of clinics treating the diseases:

Duodenal cancer:

Related procedures:

Duodenal Cancer: Overview and Treatment Options

Disease Types & Epidemiology

How common is the disease?

Duodenal cancer is an uncommon type of malignant tumor that starts in the duodenum, the first segment of the small intestine. The duodenum is a vital part of the digestive system, linking the stomach to the jejunum and helping to break down further the food we consume. This cancer is a rare form of small bowel cancer, which makes up approximately 3% of all gastrointestinal cancers. According to the National Cancer Institute data, around 12,500 new cases of duodenal cancer arise each year. Together with a 70% average five-year survival rate, the estimated number of patients living with duodenal and other part of small bowel cancers in 2021 was around 83,500 individuals in the US [NCI, 2024].

Epidemiologically, duodenal cancer is more frequently observed in older individuals, typically those over the age of 60, and has a slightly higher incidence among men compared to women. However, the scarcity of comprehensive epidemiological data on this rare cancer can be attributed to the nonspecific nature of its symptoms, which often leads to delayed diagnosis and detection at more advanced stages (61% of cases).

Duodenal cancer can take on different histological forms, with adenocarcinoma being the most prevalent. This type originates from the glandular cells lining the duodenum. Other, less common types include sarcoma, which arises from connective tissue cells; neuroendocrine tumors that develop from hormone-producing cells; and lymphoma, a cancer that begins in the lymphocytes, a type of white blood cell.

Causes & Risk Factors

What is the primary issue of duodenal cancer?

The exact causes of duodenal cancer remain unclear, but several factors have been identified that significantly raise the risk of developing this rare malignancy:

  1. Genetic factors: inherited conditions like Familial Adenomatous Polyposis (10% lifetime risk) and Lynch Syndrome (3-6%) are strongly linked to an increased risk of duodenal cancer.
  2. A diet high in fat and low in fiber, including large amounts of red and processed meats, can increase the risk by 18-21%.
  3. Chronic inflammation during conditions like Crohn's disease and celiac disease, which cause ongoing inflammation of the digestive tract, can raise the risk of duodenal cancer by up to 4 times. Chronic inflammation may lead to changes in the cells lining the duodenum, making them more susceptible to cancer.
  4. Smokers have about a 50% higher risk compared to non-smokers, and heavy alcohol consumption can increase the risk by around 20-25%.
  5. Men are slightly more likely to develop this cancer than women, with a male-to-female ratio of approximately 1.5:1.
  6. Being overweight or obese has been shown to increase the risk of duodenal cancer by about 30%.

Clinical Manifestation & Symptoms

What signs should one anticipate while suspecting duodenal cancer?

The symptoms of duodenal cancer can be pretty vague and nonspecific, often leading to a delayed diagnosis. Patients may experience abdominal discomfort or pain, feel nauseous and have episodes of vomiting, notice unintentional weight loss, and feel fatigued. Additionally, some individuals may notice gastrointestinal bleeding or have their intestines become obstructed, resulting in severe pain and more vomiting.

Diagnostic Route

When, where, and how should the duodenal cancer be detected?

Diagnosing duodenal cancer can be challenging due to its location within the small intestine [Kanagawa et al., 2022]. The diagnostic process typically involves several key steps:

1. Endoscopy: An upper endoscopy allows for direct visualization of the duodenum and obtaining tissue samples for biopsy. This is a critical tool for diagnosing duodenal cancer, which is divided into two options:

1.1. Double-balloon enteroscopy is an advanced endoscopic procedure that enables a more profound exploration of the small intestine, including the duodenum, and can be especially helpful in diagnosing obscure gastrointestinal bleeding.

1.2. Capsule endoscopy uses a visualizing technique involving swallowing a small, camera-equipped capsule that takes numerous images as it travels through the digestive tract, providing valuable insights into areas that are difficult to access with traditional endoscopy.

2. Imaging studies are chosen depending on the potential tumor stage and spreading status:

2.1. CT scans and MRIs provide detailed images of the abdomen and help determine the cancer stage.

2.2. Endoscopic ultrasound combines endoscopy and ultrasound to offer detailed images and assess the depth of tumor invasion.

2.3. PET scans detect cancer spread to other body parts.

3. A biopsy is a histological examination of the lesion samples that confirms the diagnosis and helps determine the type of duodenal cancer.

Treatment Approaches

What are the options for managing duodenal cancer?

Surgery, chemotherapy, targeted therapy, and immunotherapy are the four core treatment methods for different stages of duodenal cancer [Cancer.gov, 2024].

The surgical approach leads to the most outstanding curative results in localized duodenal cancer due to its radical removal of the whole tumor lesions by one of two procedures:

  1. Pancreaticoduodenectomy, also known as the Whipple procedure, is the most common surgery for duodenal cancer. This operation involves removing the duodenum, a portion of the pancreas, the gallbladder, and part of the bile duct. Despite its complexity, this procedure has a high success rate for treating localized duodenal tumors, with a five-year survival rate of approximately 40-60%.
  2. Duodenal segmental resection may extend to a lesser portion of the pancreas or bile duct system but is used for smaller localized duodenal tumors.

Chemotherapy is effective both as adjuvant (after the surgery in localized forms) and monotherapy in advanced duodenal cancer (5-fluorouracil, leucovorin, and irinotecan regimens). The successful therapeutic range in late-stage tumors stays in the 20-30% range of cases.

Targeted therapy (anti-EGFR – cancer cell growth factors inhibitors – erlotinib and cetuximab) and immunotherapy (pembrolizumab and nivolumab against PD-L1 immune checkpoints molecules) are reserved options with 15-20% response rate in heavily pretreated patients.

Prognosis & Follow-up

How does cutting-edge science improve the lifespan and quality of life for those with duodenal cancer?

Early-stage duodenal cancers generally have a more favorable prognosis, with around 85% of patients surviving at least five years when the disease is confined to the local area and 79% when lesions involve regional lymph nodes. Conversely, advanced-stage duodenal cancer carries a less favorable prognosis, with the five-year survival rate dropping significantly to approximately 45%.

After completing treatment for duodenal cancer, patients typically undergo a comprehensive follow-up regimen. Regular check-ups are scheduled every 3-6 months in the initial two years. During these visits, the healthcare team will conduct physical examinations, perform blood tests, and order imaging studies like CT scans to monitor the patient's progress and detect any signs of recurrence.

As the patient moves into the long-term follow-up phase, the frequency of visits may be reduced to every 6-12 months, depending on their situation and the risk of the cancer returning. This ongoing care will still include physical exams, along with periodic bloodwork to assess liver function and check for tumor markers. Additionally, imaging tests like CT scans or MRIs may be scheduled annually to thoroughly evaluate the patient's condition and ensure no concerning changes.

  • Alejandro Santos, M.D.
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